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Questions & Answers

If you have any questions about PCOS, it’s effects or it’s treatment that you would like an answer to, please leave them in a comment on this page and I will do my very best to provide you with an answer in as short a time as possible.

In the meantime, I hope you will learn something new and useful in one of the questions already answered:

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18 comments to Q & A

  • Jenee

    Can you send copies of all the studies that have been done on DCI in the medical and scientific journals or clinical trials so that I can educate my RE at my next appt.

  • Jenee

    Nevermind. I found the requested information under Natural Treatments and not under News and Research.

  • N

    Dear Anne,

    I checked for pregnancy and as usual it was negative. I spoke to my doctor and she asked me to buy Chrominac A by TTK. I told her that my acne is getting worse with Myo inositol so she asked me to quit it for a few days and then come meet her again. Please tell me what chrominac A is? I really feel like a guinea pig being experimented upon with no solution at hand. In the end it’s just making me frustrated. As of now my doctor is only prescribing me natural supplements instead of hormonal medicines which is a good thing but I am no longer sure if anything is really helping…

  • My PCOS Info

    Dear N,

    I’m sorry you had to check for pregnancy again to determine what is causing your symptoms. I know it’s an emotional roller-coaster ride, even if you expect the result to be negative.

    It seems exceptionally peculiar to me that your doctor is recommending various brand names for each type of supplement.

    You would need to be off the myo-inositol for at least a month to determine whether it was having any effect on your acne. A few days will not provide a definitive answer one way or the other, unfortunately.

    ChromiNAC-A is an Indian brand of vitamin supplement with chromium, N-Acetyl Cysteine (NAC), a type of vitamin D analogue and biotin in it. These ingredients may help treat some of the symptoms of PCOS, but they are not addressing the cause – functional DCI deficiency, and the dosage is not being appropriately titrated to your specific requirements.

    Chromium is an essential trace mineral that is significantly involved in carbohydrate metabolism – at 1000 mcg per day can help improve insulin sensitivity and glucose disposal. These tablets only have 500 mcg, which is not sufficient.

    N-Acetyl Cysteine is formed from an amino acid (the building blocks of proteins) and is an antioxidant which also has insulin sensitising properties. It can help reduce biochemical markers of PCOS, but only in women who are insulin resistance and hyperinsulinaemic. When taken in combination with clomiphene citrate (Clomid) it improves the rate of pregnancy in clomiphene resistant women with PCOS.

    Biotin is a B vitamin which is necessary for metabolism and growth in humans. It stimulates liver glucokinase activity, increases insulin production and enhances glucose uptake in muscle cells. It is often taken by women with PCOS to help hair growth, but it’s a double-edged sword – it increases hair growth everywhere, not just on your head, and in women with PCOS it is frequently reported that it increases unwanted hair growth as well. Generally, the amount in a multivitamin or B-complex vitamin supplement is sufficient to address any deficiency without risking the unwanted side effects.

    Alfacalcidol is rarely used (mostly as a supplement in chicken feed) and I am unable to determine an equivalency between it and hydroxyvitamin-D3, so I don’t know whether the amount is sufficient or not. Vitamin D supplementation is highly individualised, however, and reputable practitioners always supplement Vitamin D3 by itself in a dose which has been titrated to the particular patient’s needs. An appropriate amount of Vitamin D3 supplementation might be anywhere from 1000 I.U. to 20,000 I.U. per day. It is important to correlate with blood test results at baseline and monthly ongoing until the appropriate dose has been determined.

    I sympathise with you feeling like a guinea pig. My recommendation is to educate yourself about PCOS, it’s etiology, pathology and treatment so you are in a better position to make your own decisions and evaluate whether the advice you are receiving is good, bad or mediocre.

    Ultimately, if the advice your doctor is giving you is not helping, you may need to seek another doctor.

    I sent you the peer-reviewed published scientific studies describing how women with PCOS are deficient in DCI and the findings that supplementing with 1200 mg of DCI per day resolved the symptoms in 86% of those women, didn’t I?

    I also recommend that you read:

    Best wishes,


  • D

    Hi Anne

    How many days will it normally take to get the DCI supplement after placing order ? I stay in Singapore


  • My PCOS Info

    Hi, Normally less than 2 weeks, sometimes less than one week.

  • I am 38 years old.i have no child.not a single doctor prescribe chrominac a tablet,but I cannot found it in doctor is no more.i want know chrominac a is which group of this tablet? do you know another name of this tablet.dont lough,i don’t know more English.

  • GM

    I found your website while searching for natural ways to prevent male baldness. What an amazing resource you have assembled here! Thank you. Upon reading the benefits of DCI for women, many of them sound like they would be equally beneficial for men (triglycerides, blood pressure, increased insulin sensitivity etc). Is DCI only effective for women or would it also benefit men as well? Does DCI reduce conversion of testosterone to DHT?

  • beth

    can i get rid of pcos? i am 28..ive had two children. my son is 3yo and my daughter is 19months.. i have belly obesity..apparently my blood test showed insulin was normal (however i think i screwed my blood work up bc i drank wine the night before the test) my cholesteral was up also…which im constantly on a diet and not over weight..but getting there in the belly area for sure. my ultra sound was clear with the “pearl effect” that my obgyn couldnt have been more clear that i do infact have pcos.. i dont have facial hair, acne, oily skin etc..all i have are long cycles (40-45days, painful periods/heavy bleeding..weight gain specifically in the belly area(like i look 6months pregnant)) im almost in denial that i have this..and why all of a sudden.. any insight?

  • My PCOS Info

    Hi Beth,

    Your symptoms do sound very much like they are related to insulin resistance, though there can be other causes than PCOS. Perhaps your doctor did not do the right tests? Insulin resistance is harder to pick up than glucose intolerance, which is generally what the oral glucose tolerance test is designed to catch. To pick up insulin resistance with an OGTT, it is best to take samples every half hour and test both glucose and insulin at each time point. It is also important to keep testing for at least an hour after the blood glucose level returns to ‘normal’ in case hypoglycaemia follows, as that is indicative of insulin resistance, even though the test values may remain within normal limits.

    If you do have PCOS or insulin resistance, please look into d-chiro inositol and perhaps Glucorein.

    PCOS can occur without polycystic ovaries and polycystic ovaries can also occur without PCOS. It’s a very misleading name for a complex endocrine condition. Not all women with PCOS have the typical symptoms. Some have very few symptoms. It is a spectrum disorder and effects can range from imperceptible to incapacitating.

    It may be worth seeing an endocrinologist, rather than an OBGYN, as PCOS is an endocrine disorder with gynaecological symptoms and effects. An endocrinologist may be better placed to diagnose it accurately and help you understand what it is all about and what you can do about it.

    Good luck and if you have any more questions, please let me know. I’m here to help.

    Kind regards,


  • My PCOS Info

    Hi G,

    Thank you very much for your comment. I’m glad you’ve found the information helpful.

    The effects of d-chiro inositol on blood glucose metabolism and therefore triglycerides, cholesterol, inflammatory markers etc occur irrespective of gender, so in relation to improving disordered blood chemistry which is a result of insulin resistance and which tends to occur as we age in both genders, DCI would be equally beneficial.

    DCI does not directly reduce conversion of testosterone to DHT, it influences insulin metabolism, much, much further upstream, which, in women, reduces the production of testosterone from the theca cells in the ovaries. I doubt that DCI would affect male pattern baldness in men.

    Kind regards,


  • My PCOS Info


    I’m sorry, I know very little about Chrominac-A, other than it is a proprietary vitamin supplement designed for PCOS and that it contains N-acetylcysteine, Chromium and a form of vitamin D which is very rarely used in humans as well as some biotin. Another viable alternative is to take Chromium, N-acetylcysteine and vitamin D supplements separately. I don’t know where you can buy Chrominac-A from, nor do I think there is a strong case for recommending it.

    If you have any more questions, please let me know. I’m here to help.

    Kind regards,


  • Salinity

    I have been using chrominanc A for a year for heavy periods.Thank God..much improved

  • Mariam

    I am 18 years old. Almost 4 years ago I started my struggle with weight loss until 6 months ago, I went from almost 90 kgs to 57 kgs. my period stopped almost 2 years ago but I thought that was normal because of the weight loss and exercise and all. But 6 months ago ( without changing my eating habits) my weight kept going up again until 75 kgs. I went to an OBY/GEN she told me I had Multiple cysts on my ovaries, and I went to a nutritionist to find out that my fat percentage fluctuates like crazy, sometimes I am puffed because of water some times it’s fat and sometimes it’s both, other than that, my facial/body hair has increased.
    I don’t know what is wrong with me but I do know that the past 3 and a half years that I spent trying to lose weight were the hardest years of my life and I hate to see all that pain go to waste.
    all my tests are within normal ranges except
    LH is SLIGHTLY more than FSH
    Progesterone is relatively too low

  • Christel

    Hi,can one have poly-cystic ovaries without having PCOS?

  • Christel

    My daughter had the Jadelle inserted in her arm (used to be called Norplant in America). She stopped menstruating all together and had a real bad stomach ache not long ago which required a trip to the A&E. She was diagnosed with PCOS and I had a sneaky suspicion it had something to do with the Jadelle. After investigating I learned that quite a few people have developed poly-cystic ovaries after using the Norplant/Jadelle. It is not used/marketed in the States anymore but is now widely used here in NZ (subsidized by our government.
    There is nobody in both our families (dads nor mums side) that has PCOS. We were told it is genetic. I believe she developed cysts on her ovaries because of this Jadelle. Have you heard or know anything about this?
    Or can you develop cysts on your ovaries without being PCOS. Blood tests came back OK but apparently they did not test for testosterone levels.

  • My PCOS Info

    Absolutely! You can also have PCOS without having polycystic ovaries, so it’s a thoroughly confusing name for the condition.

  • My PCOS Info

    Hi Christel,

    I’m so sorry to hear about your daughter. I’ve heard an awful lot of stories from women who developed PCOS after birth control. There is some early research linking birth control to the development of PCOS, which is not surprising. The quantities and concentrations of hormones in birth control are just horrific in my opinion and cause many problems for many women. One well known side effect of most oral contraceptives is a worsening of insulin sensitivity which also happens to be the cause of PCOS.

    The proper tests to perform if PCOS is suspected are here:

    Testosterone is most certainly one of them. It’s also very important to check her insulin sensitivity via a 2 hour glucose tolerance test WITH insulin levels at all points.

    Whilst there is certainly a genetic basis to PCOS and in fact everything about our health, our environment and how we interact with it and what we are exposed to within it play a very important role. If there is no other family history of PCOS, type II diabetes or metabolic syndrome, then it is likely that the genetic component is of far less significance in your daughter’s case than was the exposure to the synthetic hormones in the implant.

    If there’s any other information I can help you with, please let me know.

    Kind regards,


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