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D-Chiro Inositol & D-Pinnitol

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Buy DCI D Chiro Inositol for PCOS polycystic ovarian syndrome now




DCI D-chiro-inositol for PCOS Polycystic Ovarian Syndrome

D-Chiro-inositol increases the action of insulin in patients with the polycystic ovary syndrome, thereby improving ovulatory function and decreasing serum androgen concentrations, blood pressure, and plasma triglyceride concentrations.”

This is the exciting conclusion reached by Dr Nestler and his team of researchers.

Effects of DCI in PCOS




Buy DCI D Chiro Inositol for PCOS polycystic ovarian syndrome now

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What is DCI?

How Safe Is It?

Why Is DCI Important for PCOS?

What Research Has Been Done?

How Much Should I Take?

What Do Women Who Have Taken DCI Report?

Inositol Hexaphosphate (IP-6)


Sources of DCI

Links to DCI Information Resources

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44 comments to D-Chiro Inositol & D-Pinnitol

  • Ashley

    I am currently obtaining my Masters in Dietetics and Nutrtion and have been trying to compound enough data on the benefits of inositol for PCOS.
    I am trying to put together a study and intervention for PCOS patients that will focus on dietary changes as well as natural supplementation focusing on the inositol family.

    Any information would be very helpful as I would love to help in my quest to make life and pregnancy much easier for us all.

    Thank you for all your research!

  • Ashley,

    Thank you for your kind comments – it really makes spending all the time and effort researching this and putting this website together worthwhile, to know that there are people out there whom it is helping.

    The reference section at the bottom of pages or, if I have been especially longwinded as in the DCI article – the Links to Resources page: is a good place to start … when you have a solid week to read it all :)

    I will email you with copies of some of the relevant studies that I have saved.

    Do let me know how you go, and if there’s anything I can do to assist with the study. I studied Orthomolecular Nutrition and did a post graduate Diploma in Clinical Nutrition about a million years ago myself … it’s a very interesting field.

    Kind regards,


  • Sam

    Hi, how can I order some of this DCI from you?

  • Hi Sam,
    It’s easy, all I need is an email telling me:

    * Your full name
    * The address you want the DCI posted to
    * How many grams of DCI you would like (it doesn’t have to be a multiple of the 18 g packets, I can measure out a custom quantity based on your needs)
    * Whether you would like the DCI sent via regular mail, express post or registered mail.

    I will then send you a quote/invoice and payment details and if you are happy with it, once you have paid for it, I will ship it that same day. I can accept payment via Paypal (though there is a small extra charge to cover their fees), or direct deposit into my Australian bank account or by telegraphic transfer from an overseas bank account.

    Too easy!

    I look forward to hearing from you again.

    Kind regards,


  • Lindsey

    What is the recommended dosage with the DCI powder? I was told that if your weight is under 130lbs/60kilos, you should take 600mg in capsule form and if you are over, to take 1200mg. Is the dosage different with the powder?

  • As DCI is still the subject of clinical trials, it is a little too early to say what ‘the recommended dosage’ is. The information you have been given has likely been tailored by a company that sells DCI in 600 mg increments. As with most drugs and supplements, the right dosage for each individual will vary based on a number of factors such as age, weight, the amount of carbohydrates consumed and the type (low or high GI).

    The earlier studies ten years ago were based on a dose of 1200 mg DCI once daily in the morning for overweight women and 600 mg once daily in the morning for lean women, and this is likely where the advice you received about the capsules came from. The more recent studies and clinical results have been trialling amounts up to 3000 mg per day and in divided doses rather than once daily.

    Therefore, the current recommendation, whether for powder or capsules as they are essentially identical, is to take between 10 and 20 mg per kilogram of your bodyweight per day in two or three separate doses. This is much easier to achieve with the powder as you can measure out precisely how much you should be having at each time, rather than having to ‘make do’ with 600 mg capsules.

    For instance if you weigh 132 lb or 60 kg, you could take between 600 and 1200 mg per day. If you weigh 220 lbs or 100 kg your recommended daily therapeutic dose would be between 1000 mg and 2000 mg.

  • Lindsey,

    I will write back to you personally and attach some studies for you, but essentially I personally feel it is better to have the pure DCI powder without all the fillers etc as they can have a negative effect on digestion, causing nausea in some cysters. The active ingredient is identical – in fact I believe it is manufactured by the same chemist.

    Kind regards,


  • Lindsey

    Dear Anne,

    Thanks so much for such a swift reply! You’ve answered a lot of my questions
    effectively with just one simple email.

    I would be interested in seeing any of the studies you might have at your
    disposal, if it is not too much of an inconvenience. I guess my last
    question would be your opinion of the quality of the powder versus the
    capsules. I was looking into Chiral Balance capsules, but recently found
    some information about ‘filler’ put in the capsules that dilutes the actual

    Thanks again,

  • moredd

    I believe the chiralbalance has 0 fillers and is using a mushroom gelatin based capsule that is proven not to interfere.

  • Vivi

    I need know how can I Order D-Chiro and how much is , I am at Kansas USA – Thank you!

  • Hi Vivi,

    DCI is $30 AUD for 18 grams, $150 for 100 grams ($25 per 18 grams) or $280 for 200 grams ($21.60 per 18 grams). This equates to between $1.40 and $1.67 per gram and is the cheapest DCI being retailed in the world at present, to the best of my knowledge.

    Postage rates to the USA for 18 or 36 grams by regular airmail is $2.40 AUD. 100 grams costs $4.60 by regular Airmail and 200 grams costs $7.10. Registered Mail costs $20 AUD for up to 500 gm.

    If you send me an email to with the amount you wish to order and the type of postage you require (regular Airmail or registered) I will send you a Paypal invoice which you can pay from either a bank account or credit card without the need to sign up for a Paypal account.

    I look forward to hearing from you.

    Kind regards, Anne

  • an

    Hi, a few questions.

    1. Where is it manufactured?
    2. What are the company’s details – name, are they registered etc?
    3. What is it manufactured from?
    4. Where do you import it from?
    5. Does the manufacturer provide a guarantee that is is DCI and pharmaceutical grade? Can you make this available to your customers?
    6. What benefits have you found from taking it and how long had you being taking it before you found it helpful?
    7. What other treatments do you take and why?

    Thanks for taking the time to reply.

  • Melissa

    Hello :)
    Tonight I went to a new doctor who recommended I visit your website to read about dci for a pcos problem I’ve have for 15 years. I’m at the stage in life where I want to try and fall pregnant. I haven’t had a period in years…. the doctor prescribed me progesterone which I will start taking tomorrow…and I was thinking ill combine it with dci. I have a few questions though….
    1.Can I take the two together?
    2. Is science safe to take once pregnant?
    3. What dosage are u required to take… how long will 18 grams last
    And 4. How is it consumed???
    Sorry for all the questions, this is all very new to me!!
    Thanks for your help.

  • My PCOS Info

    Dear Melissa,

    Thank you for your email regarding DCI. I’m very glad to hear that
    your doctor referred you to my website and I’m happy to answer any questions that you or they might have.

    Let me answer your questions in the format in which you asked them:

    1. Yes it is safe to take progesterone and DCI together, in fact I do
    so occasionally myself. DCI’s primary mechanism of action revolves
    around insulin signal transduction and through it carbohydrate
    metabolism. If you take DCI, you may not require progesterone after a
    few months, but this is something for you and your doctor to monitor
    together. Progesterone levels are low in women with PCOS ultimately
    because of hyperinsulinaemia. Once this is addressed, through
    increasing insulin sensitivity or DCI supplementation, progesterone
    levels should increase again. I’ve attached some studies which found
    this to be the case. You may find them interesting, or you may wish
    to take them to your Dr for them to read.

    2. This is a difficult question to answer categorically. It’s a very
    personal choice. All I can do is tell you what I know and what I
    would do if I were pregnant. There have not been, nor are there ever
    likely to be, studies done on the safety of DCI during pregnancy. As
    it is not patentable, being identical to a substance manufactured in
    nature, there is insufficient monetary incentive for anyone to fund
    these studies. On the other hand, I can tell you that:

    DCI is a substance found in healthy human bodies, which plays a
    critical role in carbohydrate metabolism through the insulin
    signalling pathway.

    We take supplemental DCI because women with PCOS/IR etc appear to have
    a defect in inositol metabolism which prevents us from obtaining DCI
    from food, manufacturing it from inositol in vivo and also makes us
    excrete whatever DCI we do manage to obtain many times more quickly
    than other human beings. In summary, we are restoring the status quo,
    rather than taking a nutrient in doses larger than normally obtained
    through the diet in order to achieve a pseudo-pharmaceutical effect.

    DCI is naturally derived, close to 100% pure chemically and is
    something that can be found in some foods.

    By regulating carbohydrate metabolism and normalising elevated insulin
    and blood glucose levels, DCI helps to balance female reproductive
    hormones, by preventing the inhibition of progesterone production
    which occurs with elevated levels of testosterone (a side effect of
    elevated insulin levels). Progesterone is essential for sustaining
    pregnancy. It is the ‘pregnancy hormone’. If there is insufficient
    progesterone, miscarriage is likely. Progesterone insufficiency is
    the leading cause of miscarriage amongst women with PCOS. The
    placenta will takeover progesterone production from around the 12th
    week, which is when the risk of miscarriage is greatly reduced.

    During pregnancy, insulin sensitivity is dulled in everyone, not just
    those with PCOS/IR. All women are at higher risk of diabetes during
    pregnancy or in later life partially as a result of pregnancy.
    Gestational diabetes is usually transitory, resolving after birth,
    however, it increases the risk of diabetes in later life for both the
    mother and the child. Elevated insulin and blood sugar levels during
    pregnancy have a negative effect on the foetus.

    I cannot advise you on the right course of action – this is a decision
    that ultimately only you can make, in conjunction with your doctor.

    All I can do is share with you what I would do. If I were pregnant I
    would definitely continue taking my DCI. I consider it likely to be
    an exceptionally safe substance. I believe that the risks of not
    taking it vastly outweigh any potential risks of taking it.

    3. Clinical results indicate that an initial dosing regimen of at
    least 20 mg per kg of bodyweight is required to effect results. For a
    60kg (132lb) woman this would be 1200mg per day. On this dose, 18g
    will last for 15 days. For a 90kg woman (198lbs) this would be 1800mg
    per day. On this dose 18 g will last for 10 days.

    4. I sell DCI as a powder with a little custom measuring scoop which
    measures out 100mg of DCI. It’s easier to take an appropriate dose
    for your bodyweight this way and the DCI tastes very much like sugar.
    Given that we have to be incredibly strict with everything else sweet,
    it seems like a wasted opportunity to hide something so delicious away
    in a capsule and it also saves on packaging and postage, making it
    cheaper for you as well.

    On a personal note, I had not had a period for 3.5 years when I first
    discovered DCI. I had one four weeks after I started taking 1200mg a
    day (at the time I required more than this, but was not aware of the 20mg/kg recommendation) and my cycle has become progressively more
    regular since then. I hope it will work for you as well.

    If you or your doctor have any further questions, please let me know.
    I’m here to help.

    Kind regards,


  • Brooke

    Hi Anne, thanks for the info and support. I just wanted to give you a quick update on how I’ve been going since starting DCI three months ago. I wish I could tell you that I’m pregnant but unfortunately that hasn’t happened yet. But I know that the DCI is helping me. I noticed a difference in my acne in the first week. Now after three months my skin is almost perfectly clear. I cannot remember the last time it looked this good! I have been having regular cycles and blood tests in the last two months have confirmed that I have ovulated in those cycles. I’ve also noticed a positive effect on my moods. They seem more stable. I hope one day soon I can report back that DCI has helped me get pregnant. But in the meantime I know it is helping to balance my hormones and is helping me to look healthier and feel better about me. Thanks again for distributing DCI in Australia. I only wish I discovered it earlier. Take care, B

  • My PCOS Info

    Thanks Brooke! I’m glad to hear that you are noticing so much improvement. Good luck for next month! Anne

  • Melanie

    It’s been a while since I’ve been to your site and I just wanted to let you (and your readers) know my news. My husband and I tried IVF for over 10 years after trying to conceive unsuccessfully by ourselves for 3 years. We had given up all hope of having a child of our own when I found your website.

    After you explained to me how DCI works and what causes PCOS, I ordered it from you and started taking it in June of last year, thinking that we might try one more IVF cycle after giving my body a few months on the DCI.

    I had a period in July, five weeks after I started taking DCI, then nothing. I was very disappointed as I was hoping that the DCI would help to regulate my cycle. I went to the doctor in September for some progesterone to bring on a period and when she heard I had been taking DCI, she insisted on doing a pregnancy test first. It was positive! She sent me for an ultrasound and I discovered that I was 10 weeks pregnant. I could not believe it. We have waited so long for this, tried so many things and spent an absolutely horrific amount of money on IVF and fertility specialists and in the end, the solution was a simple as a nutritional supplement that costs less than $100.

    After talking to you, I decided to keep taking the DCI throughout my pregnancy to ward off gestational diabetes and keep my energy levels up. I think that this was the right decision. I seemed to coast through the pregnancy with very little trouble, despite being 37 years old. Our beautiful baby girl, Susannah, was born in April and she is now almost 6 months old.

    Words cannot describe how grateful I am to you, Anne, for all the information, support and encouragement you have given me and ultimately, for giving us the daughter that we never thought we would have.

    I plan on taking DCI for the rest of my life. Now that I am no longer pregnant, I can fully appreciate how much better I feel taking it. It’s like the fog has been lifted from my mind and my energy levels are so much better. I don’t crave sweets or carbohydrates any more, I’m not constantly hungry and I have a regular period for the first time in my life. I no longer get acne along my jaw and chin, which I’ve had all my adult life and the hair on my aface no longer grows back after laser treatment.

    I just wish that someone had told me about DCI 20 years ago, it could have saved me so much heartache.

    Thank you, Anne, from the bottom of my heart.

  • Brooke

    We went to see a fertility specialist last month and she said that if I had been to see her last year she would have put me on Clomid and Metformin to regulate my cycle but she said I seemed to have done that on my own. So that’s another pat on the back for DCI. Thought you might like to know! Take care, B.

  • Sandy

    In 2007, my husband and I began trying to concieve our 2nd child. I’ve struggled with PCOS since I was 15 and conceived our first child with progesterone and clomid. In 2007 I began taking progesterone and clomid. For some reason, my body didn’t respond this time. I didn’t ovulate at all and after trying month after month (and upping the dosage of clomid) my doctor told me that he would have to refer me to a specialized clinic 70 miles away. My doctor had me on the fertility medication (on and off) for 24 months. I remember dialing the number to the fertility clinic thinking that it would be too difficult to get to work (I teach) and drive 70 miles (one way) to the clinic. I asked the receptionist a few questions and hung up. That evening my husband and I discussed our options. We decided to research PCOS and try everything we could to make me as healthy as possible and to try herbs. That’s when I stubbled upon Anne’s site. In Oct 2009 I ordered 3 months worth. In November 2009 I started taking vitex and DCI. Two weeks after starting the DCI, I had a period. 6 weeks after starting DCI, I had another period. 10 weeks after starting DCI, I was expecting another cycle and was so disappointed when it didn’t come. I remember crying to my friend that I hadn’t gotten another cycle. She suggested a buy a pregnancy test. I was pregnant! Ten weeks on DCI and I was pregnant! I delivered a healthy 7 lb 15 oz baby girl on September 26, 2010. She’s a smart, independent 2 year old now. If you’re reading the information on this site and asking yourself if DCI can help, I’m here to tell you that it can. Thank you Anne for helping me complete my family. I can’t imagine life without my Helena.

  • My PCOS Info


    Thank you so much for sharing your story! I’m so glad to have been able to help in a small way and I am so glad you have decided to take DCI again to normalise your health and maximise your chances of being there for your family in good health for as long as possible.

    Conceiving and having a baby is only the first step, the next stage is remaining present and having the energy to nurture your family into the future. Life is not always easy for women with PCOS, we often have very low energy levels because of our inability to efficiently metabolise carbohydrates and turn them into energy at a cellular level, and the symptoms which ensue from the cascade of abnormal biochemical processes which stem from this little defect, like hair loss, obesity, infertility, excess facial and body hair and acne, are really difficult to cope with for a lot of women. The increased risk of cardiovascular and metabolic risk factors is also a serious health concern. As taking d-chiro inositol significantly reduces these risk factors, as well as other symptoms of PCOS, DCI should be a part of everyday life for women with PCOS, long-term. I intend to take DCI for as long as it is available to me, because of the following:

    Women with PCOS have higher rates of miscarriage, gestational diabetes, pregnancy-induced high blood pressure (preeclampsia) and premature delivery.

    Babies born to women with PCOS also have a higher risk of needing to spend time in a neonatal intensive care unit, or of dying before, during or shortly after they are born, although mostly these things happen in multiple births such as twins or triplets, as a result of fertility treatments.

    Studies have found that treatments which normalise insulin sensitivity and glucose disposal, like d-chiro inositol, improve the chances of a healthy pregnancy, live birth and healthy child.

    Women with PCOS are at greater risk of developing several serious health conditions, including life-threatening diseases. Recent studies have found that:

    More than 50 percent of women with PCOS will have diabetes or pre-diabetes (impaired glucose tolerance) before the age of 40.

    The risk of heart attack is 4 to 7 times higher in women with PCOS than women of the same age without PCOS.

    Women with PCOS are at greater risk of having high blood pressure, high levels of LDL (bad) cholesterol and low levels of HDL (good) cholesterol.

    They also have a higher risk of sleep apnoea, a condition where the airways temporarily close at night during sleep and breathing stops for a period of time.

    Anxiety and depression are also common in women with PCOS.

    Irregular menstrual periods may also increase the risk of endometrial and breast cancer, through not shedding the endometrium (womb lining) frequently enough, and also because when ovulation does not occur, the body continues to produce oestrogen instead of switching to progesterone during the second half of the cycle. This oestrogen dominance also increases the risk of certain types of cancer.

  • Wolf

    I have recently been diagnosed with type 2 diabetes and have lost 29kg (much of it muscle mass) at an alarming rate. Currently I am on 16 units of insulin before breakfast and 16 units before dinner.

    My blood sugar level hardly went below 20. I started taking DCI yesterday before dinner.

    This morning my sugar level was down to 14.6. At lunch today, after another dose of DCI in the morning, I measured a low 9.4.

    My sugar level hasn’t been that low for months.

    Early days, but I’m exited about the prospects.

  • Jane


    Last year I was diagnosed with pcos after an ultra sound scan.
    I have been trying to get pregnant for nearly a year but its not happening.
    Am trying for my 3rd child and didn’t struggle conceiving my other 2 who are 7 and 3 years of age.
    I have been taking vitex for the last 3 weeks and am hoping it’ll regulate my chcle.
    Also wanted to say am 40 years old. I suffer from
    Lower abdominal pains caused by an enlarged ovaries, very bad PMS, mood swings, weight increase, low energy. Do you think a combination of vitex and DCI would help?

  • My PCOS Info

    Hi Jane,
    Yes, there is a very good chance DCI and vitex will help you. They work very well together. DCI addresses the cause of the insulin resistance (which in turn causes the hormonal abnormalities that eventually result in polycystic ovaries) and the vitex gives your body an extra push to realign your hormones and get everything working in a rhythm again.
    Good luck!

  • Cecilie

    Dear Anne,

    Your website seems as the thing I have been looking for since I was diagnosed with PCOS ten years ago. I have tried so many different ”cures” and spend a lot of money, time and worry. Your way of communicating the knowledge about the condition, the science that has been done and your experience makes me feel in the best hands ever!

    I have started taking the Vitex Agnus Castus, but I am a bit insecure about the dosage. I take this product:
    And I take one scoop right after getting out of bed in the morning. Is that the right way to go Anne?

    I have struggled with depression many times, and I often feel like my hormones “play” with my mind. I stopped taking p-pills about 7 weeks ago after taking them for ten years.
    I hope the DCI could help my get more balanced and make everyday life a little less struggle.
    Then some practical questions about the DCI:
    - I live in Denmark. Is it possible to send the DCI that far?
    - And will there be expensive taxes to pay?
    - Will it be best to buy a lot of the product at one time?
    Sorry about all the money talk, but as a student they come in small portions?

    I’m looking so much forward to hear from you and hopefully get started with the DCI.
    Kind regards from Cecilie

  • I have PCOS and i am trying the insulite system and after 2 months taking it a got my period, but i stooped taking GlucX because is giving me a lot of headaches and make my hart go really fast and i can not sleep well and i am wondering if i can start taking D-Chiro Inositol for insulin resistance and if yes how much should i take my weight is 160

  • Fatima

    Hi, i’m struggling with pcos and i am very sad because whatever i do i can not lose weight, i am in the insulite but i feel without energy my humor is so bad sometimes my muscles hurt and i get a lot lot of headaches like 3 to 4 times per week i am tired of this.. well i really wanna star taking DCI and i am wondering how much should it take my weight 162 and if i have to reduce the dosage once i start losing weight. Also, is safe to combine DCI with the insulite sistem?

  • My PCOS Info

    Hi Fatima,

    Thank you for your comment and apologies for the delay in replying to you. That’s rather frightening the side-effects you were getting from Gluc X, I’m surprised. It sounds like a wise decision to stop it. You can certainly take DCI with the insulite system, I’ve often wondered why they don’t include it, when they do put in some rather odd and obscure ingredients at very small (and likely non-therapeutic) doses.

    The recommended dose of DCI is 20 milligrams per kilogram to begin with.

    If you weigh 160 kg the recommended starting dose would therefore be 3.2 grams or 3200 milligrams per day.
    If you weigh 160 lbs, this equates to 72.5 kg so the recommended starting dose would be 1.45 grams or 1450 mg per day.

    If you have any more questions please let me know. I’m here to help (when I log on!)

  • Christine

    I have recently been diagnosed with PCOS and I am nearly at my witsend with this damn bleeding. I have been bleeding for 2 months straight now and I am literally falling apart from it. My gyno put me on some birth control pills but they arent doing squat. After finding this website and reading everyones testimonies to thosee who have tried this stuff, I really think as soon as I get paid, I will be buying some. Will this help to lose some weight? Im also still a lil confused on how much I would need to take daily, but I’m sure ill figure it out. Thank you ladies so much for your wonderful stories and words of advice, you have all helped my decision greatly!

  • My PCOS Info

    Hi Christine,

    I’m really sorry to hear you are having such a hard time at the moment. I’ve never had that kind of bleeding myself, but I do know how draining just a short, heavy period can be.

    DCI has helped me to lose weight, and I’ve heard from many of my customers that they have lost weight after they start taking it, but not everyone does. The best example I can recall (and I so wish this was me, but it wasn’t) was 10 kg in one month, without a single, solitary change to diet or exercise. I’m not a jealous person by nature, but I must admit to a slight twinge upon hearing this story …

    The recommended starting dose for DCI is 20 milligrams per kilogram of bodyweight. 1 kg = 2.2 lb, so a 60 kg woman weighs 132 pounds. If you need any help figuring out your dose, just drop me an email via the contact page and I’ll be happy to help you with the calculations.

    I also have a page on a few ideas to help put a stop to a monthly visitor who just won’t leave: the same page on my old site seems to get a lot more traffic and has a lot more comments, I don’t know whether any of them might be helpful to you, so I’ll include the link as well:

    Very best wishes,


  • My PCOS Info

    Hello again Cecilie,

    I think I’ve already responded to most of your enquiry when I replied to your other comment here, in particular regarding Vitex. I’m so sorry I missed this comment.

    In relation to the DCI, however, yes, it is possible to send it to Denmark. I am not familiar with Denmark’s import and Customs practices, but in general, if you order 36 grams at a time, there are no taxes to pay in most countries. This link might provide more information:

    I do give a 10% discount on the 108 gram pack size, 16% on the 216 gram pack and 24% on the 432 gram pack sizes, however, it might be best to buy in small quantities for the first few months. You can try the regular ordering service if you like, that also gives you a $10 per month discount.

    The research behind DCI and PCOS is quite substantial now, though I’d like to see more of it.

    I know, with myself, DCI has made a very big difference to my life and I intend to take it for as long as I live (or until the putative enzyme defect that stuffs our inositol and carbohydrate metabolism up is identified and a cure developed, but that may be a long, long way in the future).

    If you have any more questions, please let me know. I’m here to help and I do hope you decide to try DCI for yourself.

    Best wishes, Anne


    I purchased D-Chirol Inositol from another website. I was curious as to what the powdery substance tasted like. So I opened it up and much to my surprise it taste like PURE SUGAR. Plus I have gained at least 7 lbs and only been taking the medication for about 2 or 3 weeks. does anyone else have this same problem?

  • My PCOS Info

    Hi Milly,

    DCI does taste very similar to sugar. Weight gain during the first few weeks of taking DCI is usually due to changes in your hormone levels. Women with PCOS tend to be deficient in progesterone. DCI improves progesterone production and one of the many effects of progesterone is to cause water retention. This is why many women feel bloated during the week or two prior to their period, as it is the rise and then subsequent fall in progesterone levels which triggers the menstrual period. Of course, as DCI also improves glucose disposal within the body it is possible (though unlikely) that some instances of weight gain when taking DCI are due to that glucose winding up as fat stores. As insulin levels generally decrease on DCI, however, this latter scenario is most unlikely. Women with PCOS tend to gain weight very easily due to high levels of the hormone insulin encouraging their bodies to store all available energy as fat. When insulin levels are lowered (as in when taking DCI), this tends to stop and weight loss becomes easier, in conjunction with a controlled-carbohydrate diet and regular exercise.

    I hope this information is helpful to you Milly, if you have any more questions please don’t hesitate to ask. I’m here to help.

    Kind regards,


  • Heather

    Hello Anne,
    I just purchased “Inositol” capusules by Solaray at our local health food store today. In doing some research online as to how much I should be taking daily, I found out that Myo-Inositol and D-Chiro Inositol are two different forms that accomplish two different tasks. I am extremely overweight and have PCOS. I am also on Progesterone for the first 15 days of each month for three months due to an abnormal uterine biopsy. My doctor told me that the ultimate cure for the PCOS would be to get the insulin resistance under control by losing a significant amount of weight soon. Well, obviously, that is NOT easy for this body to do. I am on a gluten-free, dairy-free, refined sugar-free diet that is relatively low in carbohydrates. Anyway, when I called the Solaray company to find out which form of “Inositol” I purchased, I found out that it is Myo-Inositol. Will this not accomplish the same thing as you have described in all of your correspondence above? And according to your guidelines on how to decide what daily dosage to take of DCI, I calculated that I should take about 1,000 mgs three times daily. Would the same calculations be applicable to the myo-inositol? Also, I forgot to mention that I am taking Metformin 1500 units a day. Is there any conflict with metformin and inositol? I appreciate your help. This thread has been so very informative and encouraging.
    Kind regards,

  • My PCOS Info

    Hi Heather,

    There has been a little research into the use of Myo-inositol for PCOS, at a dose of 4 gm per day, no adjustment being made for weight.

    In general it seems that any benefit myo-inositol may have for PCOS is focused around fertility and egg quality, while DCI is of more use in improving insulin sensitivity and glucose tolerance.

    I personally, have not noticed any improvements at all on myo-inositol, even after months of taking it, but if I skip even a day of DCI, I can feel it.

    There is no known nor likely contraindication between either of the inositols and metformin. In fact, many women with PCOS take metformin and DCI together in an effort to manage their PCOS.

    As it sounds like you already have a handle on an appropriate diet for PCOS, adding regular exercise to your daily routine perhaps in combination with insulin sensitisers such as DCI, chromium, manganese, green tea or gymnema is likely to improve your chances of losing weight and getting your insulin/glucose metabolism back in balance.

    You can buy DCI and other supplements from here:

    If you have any further questions, please let me know. I’m here to help.

    Good luck!

  • Cheyanna

    Please tell me these testimonials are real. I’ve only been diagnosed with PCOS for about 3 years, but I’ve likely had it for ages (I’m 30 now). My husband and I would like kids, and three years into trying, I can tell you the dates of all the periods I’ve had in that time.
    I have worked my butt off getting healthy and am now at a good weight and body fat percentage (I have the benefit of being married to a personal trainer that is very supportive). My last hurdle other than pregnancy is my skin. I know it’s superficial, but it completely kills my self esteem to have the broken out skin of a teenager.
    I am up for anything that doesn’t put me on Metformin or birth control the rest of my life. Please, what do you recommend? I’ve never even heard of DCI until stumbling across this forum, and I’m sure I’m like other women here in the sense that this is not my first research rodeo on PCOS.

  • My PCOS Info

    Hi Cheyanna,

    The testimonials certainly are real :)

    DCI exerts clinically significant positive effects in 86% of women with PCOS according to the clinical studies. I take it myself and found that it restored my menstrual cycle within four weeks, when it had been absent completely for 3.5 years.

    If you have any questions, please let me know. I’m here to help.

    Kind regards,


  • Philippa

    I have been taking DCI for about a week and have noticed that I am very thirsty after taking it. The thirst seems to last most of the day. Is this normal???

  • My PCOS Info

    Hi Philippa,

    I’ve not heard anyone mention this. I actually respond in the opposite way. Before I started taking DCI, I used to drink lots of water all the time, I was constantly thirsty, which was probably an attempt by my body to dilute the excessive insulin levels (as my blood sugar was always normal). Now I have to remind myself to drink enough. It is important to have the DCI with a full glass of water to aid absorption as it is a water soluble nutrient. Do you do this? It might be better to split the dose up into three – before breakfast, lunch and dinner. As it is water soluble, it is quickly excreted by the body. In fact people with insulin resistance, including PCOS, excrete DCI in the urine faster than ‘normal’ people.

    If you have any more questions, please let me know.

    Kind regards,


  • Nonica Sharma

    I m very interested in purchasing DCI, i live in India, i would like to know if you ship to India, and if yes how should i go about placing the order.
    Thanking you
    Nonica Sharma

  • Ady S .A.

    Hello My name is Ady . I have taken DCI in the past for a month and it made me feel great. I had alot of energy and noo sugar cravings.. I started having cramps and breast were hurting. Almost like a feeling that you are about to start a period. And i have heard that you need to take it every single day without missing a day . Well i finished the bottle and i didnt go get another one like i should have. Do you think if i would of stuck with it i would of had a period.?? I am really hoping to get back on it. Bc me and my husband are ttc.. I read if you have pcos the first thing you should do is give up milk and breads and thats excatly what i did.. I am planning getting on it again.. It says it works vetter with vitamin magnese is tthis true.??what about a multivitamin .?? Pls answer or email me

  • My PCOS Info

    Hi Ady,

    It certainly does sound like you were experiencing premenstrual symptoms. Manganese definitely does improve the efficacy of DCI at lowering elevated blood sugar. Manganese doubles the efficacy of DCI

    Best of luck!

  • My PCOS Info

    Hi Nonica,

    We do ship to India. You can order from My PCOS Info Shop

    Warm regards,


  • Marissa

    2weeks ago I started taking dci. Two tablets in the morning 1200mg. I have more acne than before. I was wondering if I should up my dose to three pills aday to see if it helps. I have been attc for over 12yrs and had 6 failed iuis. This January my husband and I are trying IVF.Iam 180lbs, would three pills a day be too much?

  • My PCOS Info

    Hi Marissa,

    The recommended dose for DCI is 20 mg per kg of bodyweight, so according to those guidelines, an appropriate dose for a woman of 180 lb (81 kg) would be around 1600 mg per day. An increase in acne could be a sign that your hormones are changing, hopefully for the better. It is a common symptom in women who have not been having ovulatory menstrual cycles, when they first start taking DCI, as it increases progesterone levels which amongst many other things, tightens the pores in your skin which can lead to acne in the two weeks before a period.

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